TXNIP Stable Expression Cell Line (A549)

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  • 细胞图0 TXNIP Stable Expression Cell Line (A549)-细胞图0
  • 细胞图1 TXNIP Stable Expression Cell Line (A549)-细胞图1
  • 质粒图0 TXNIP Stable Expression Cell Line (A549)-质粒图0
  • TXNIP Stable Expression Cell Line (A549) TXNIP Stable Expression Cell Line (A549)-产品图
细胞图0 TXNIP Stable Expression Cell Line (A549)-细胞图0
细胞图1 TXNIP Stable Expression Cell Line (A549)-细胞图1
质粒图0 TXNIP Stable Expression Cell Line (A549)-质粒图0
TXNIP Stable Expression Cell Line (A549) TXNIP Stable Expression Cell Line (A549)-产品图
TXNIP Stable Expression Cell Line (A549) Copy Product Info
Catalog#： YOE-L026
Size： 1*10^6
Culture method： 90% F12K+10% FBS
STR Report
Datasheet (Use Instruction)
  • 细胞图0 TXNIP Stable Expression Cell Line (A549)-细胞图0
  • 细胞图1 TXNIP Stable Expression Cell Line (A549)-细胞图1
  • 质粒图0 TXNIP Stable Expression Cell Line (A549)-质粒图0
  • TXNIP Stable Expression Cell Line (A549) TXNIP Stable Expression Cell Line (A549)-产品图
TXNIP Stable Expression Cell Line (A549) Copy Product Info
Catalog#： YOE-L026
Size： 1*10^6
Culture method： 90% F12K+10% FBS
Datasheet (Use Instruction)

Detailed Product Information

Cell Info

Catalog YOE-L026 Transcript NM_006472.6
Cell name TXNIP Stable Expression Cell Line (A549) Species Human
Gene Name TXNIP Passage ratio 1:3~1:4
Cell Morphology Epithelial-like, adherent Antibiotic Concentration Puro=1μg/ml
Culture method 90% F12K+10% FBS Mycoplasma test negative
Catalog
YOE-L026
Cell name
TXNIP Stable Expression Cell Line (A549)
Gene Name
TXNIP
Cell Morphology
Epithelial-like, adherent
Passage ratio
1:3~1:4
Transcript
NM_006472.6
Species
Human
Antibiotic Concentration
Puro=1μg/ml
Mycoplasma test
negative
Culture method
90% F12K+10% FBS

Product Description

This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
Gene Expression Validation
No. Sample hTXNIP-1CтMean β-h_actinCтMean ΔCтMean ΔΔCт Expression Rate
1 TXNIP Stable Expression Cell Line (A549) 17.318 14.391 2.927 -13.250 9741.985
2 A549_Ctrl(Puro) 30.981 14.804 16.177 0.000 1.000
STR Profile
Download STR Report
Loci STR Info (Sample Cell)
Sample Cell Line:A549		 STR Info (Cell bank)
Cell Line:A-549
Allele1Allele2Allele3Allele1Allele2Allele3
D5S818 11111111
D13S317 11111111
D7S820 811811
D16S539 11121112
VWA 14141414
TH01 89.389.3
AMEL XYXY
TPOX 811811
CSF1PO 10121012
D12S391 1818
FGA 2323
D2S1338 2424
D21S11 2929
D18S51 1417
D8S1179 1314
D3S1358 1616
D6S1043 1113
PENTAE 711
D19S433 1313
PENTAD 99
D1S1656 1718.3
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.

Product Advantage

  • icon
    High expression
    Exclusive cell selection technique, ensuing high expression, RT-qPCR validation data provided.
  • icon
    Good stability
    Stable gene copy number, low passage, can be stably passaged for more than 20 passages.
  • icon
    Strict QC
    Strict quality control, ensuing no bacterial and mycoplasma contamination, STR authentication and cell post-thawing viability test passed; High standard delivery.
Citations:

[1] Yao, Jie, et al. "Long noncoding RNAs AC026904. 1 is essential for TGF‐β‐induced migration and epithelial‐mesenchymal transition through functioning as an enhancer of Slug in lung cancer cells." Environmental toxicology 35.9 (2020): 942-951.

[2] Roussel, L., Pham-Huy, A., Yu, A.C. et al. A Novel Homozygous Mutation Causing Complete TYK2 Deficiency, with Severe Respiratory Viral Infections, EBV-Driven Lymphoma, and Jamestown Canyon Viral Encephalitis. J Clin Immunol 43, 2011–2021 (2023).

[3] Khaodee,et al. "Transcriptomic analysis of glucosidase II beta subunit (GluIIß) knockout A549 cells reveals its roles in regulation of cell adhesion molecules (CAMs) and anti-tumor immunity." BMC Genomics 25, 82 (2024).

[4] Ding, Rui, et al. "TLR2 regulates Moraxella catarrhalis adhesion to and invasion into alveolar epithelial cells and mediates inflammatory responses." Virulence 15.1 (2024): 2298548.

[5] Yaman, Serkan, et al. "Targeted chemotherapy via HER2-based chimeric antigen receptor (CAR) engineered T-cell membrane coated polymeric nanoparticles." Bioactive Materials 34 (2024): 422-435.

[6] Wang, Liuxiang, et al. "DEPDC1 is a potential therapeutic target in lung adenocarcinoma." Nano Today 56 (2024): 102249.

[7] Wang, Juhong, et al. "Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc." Nature Metabolism (2024): 1-18.

Product Catalog#：YOE-L026
Product Name：TXNIP Stable Expression Cell Line (A549)
Related Resources: Red Cotton Gene-editing System | ATCC | DSMZ | ECAZZ | Cellosaurus | CCTCC | NCBI
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